Arsenolipids comprise a large family of non-polar arsenic compounds found in many types of seafood and seaweed. The last 20 years have seen dozens of arsenic-containing fatty acids, hydrocarbons, and phospholipids identified in seafood samples. Preliminary toxicological studies have indicated that some arsenolipids may resemble inorganic arsenic more than arsenobetaine in terms of toxicity, contrary to the reputation organic arsenicals currently enjoy as less-toxic compared to inorganic arsenic. While speciation analysis for inorganic arsenic is being employed routinely in more and more labs, those methods are not applicable to non-polar arsenic determination, and few labs are currently engaged in arsenolipid-related research. Recently at FDA, there has been increased interest in quantifying arsenic species in seafood, including arsenolipids. Initial results of FDA’s arsenolipid speciation analysis efforts will be presented as part of a general overview of this area of ongoing investigation.<br/>

Analysis of arsenolipids in seafood

254th National Meeting (2017)

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