A long history of human cannabis consumption and application, combined with a sudden and booming industry interest on the one hand, and relatively little recent, scientific research due to legal constraints on the other hand, brings us to an interesting but difficult position. It can be confusing for many to separate the wheat from the chaff in terms of understanding what cannabis effects are proven by scientific studies, which ones are based on anecdotes, or which ones are wrongly attributed to the plant or are otherwise untrue. This regards whole plant extracts and, more importantly, isolated compounds or their formulated combinations.<br/> <br/>This presentation covers the current status of our knowledge on the effects of cannabinoids and terpenes in humans. We will discuss matters such as: what factors influence human effects and why, what are the differences in effects between single cannabis compounds vs compound combinations, and what happens when you change compound concentrations or ratios?<br/> <br/>Using this knowledge, we will evaluate products that are currently on the market: why do they (not) work? We will also evaluate how you can apply pharmacological knowledge to improve products and formulations, and lastly, we will discuss the biggest unknowns in the field.

Does 1+1=3? What science really knows about cannabinoid and terpene effects in humans

255th National Meeting (2018)

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