Metal-Organic Frameworks (MOFs) are highly crystalline materials composed of organic and inorganic units. Recently, the field of MOFs has seen rapid growth due to their applications in gas separation and storage. MOFs have potential benefits for biomedical applications due to their high porosity and surface area, chemical and thermal stability, and easily tailored structures. In order for MOFs to see increased applications in biomedical fields, it is important for them to be highly stable in aqueous environments. However, the vast majority of MOFs prepared to date are not suitably stable in physiological environments. In our approach, we are preparing MOFs in water to eliminate such sensitivity while maintaining beneficial characteristics. We are particularly interested in the interactions between therapeutic compounds and MOFs in aqueous environments. This presentation examines the preparation of a variety of 2D and 3D MOFs and their interactions with guest molecules in aqueous environments.

Aqueous preparation of metal-organic frameworks for biomedical applications

255th National Meeting (2018)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.