Literature is rich in designing and producing anisotropic noble metal nanomaterials with extensive applications. But formulating a benign one suitable for medicinal purpose is an area of research yet to explore. This is a report where a one-pot synthetic methodology without any preformed seed or surfactant has been adopted yielding gold nanostructures of high anisotropy and sharpest nanoscopic features resembling ‘Hedgehog’. The morphology of these Hedgehog gold nanoparticles (HHogGNPs) can be controlled simply by changing the concentration of common ion in the medium following Le Chatelier’s principle. A contemporary Discrete Dipole Approximation for scattering calculation has been performed to understand their experimentally observed scattering and absorption pattern. These are nontoxic as detected from their MTT based study in absence of light. In addition, it can withstand high saline condition without aggregation due to salt induced synthetic modality. They show broad-band plasmon tunability and huge surface enhanced Raman scattering (SERS). The HHogGNPs, therefore, are quite apt for future nanomedicine applications.

Exploiting Le Chatelier’s principle for a one-pot synthesis of nontoxic HHogGNPs with the sharpest nanoscopic features suitable for tunable plasmon spectroscopy and high throughput SERS sensing

255th National Meeting (2018)

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