Analysis of amphetamines and their derivatives found in biological samples, such as urine, is usually done by chromatographic methods like gas chromatography (GC) and liquid chromatography (LC). The complex nature of biological samples results to the needs of using sample pretreatment methods such as solid phase extraction (SPE). In this study, chromatographic analysis (HPLC) of amphetamines was performed using sample pretreatment method utilizing two solid phase extraction sorbents namely: an HLB Oasis SPE product and a molecularly imprinted polymers (MIP). Results showed higher recovery of amphetamine in complex samples with the use of the MIP as sorbents. The HPLC results will then be compared to a GC-MS method under development.

Chromatographic analysis of amphetamines in biological samples

255th National Meeting (2018)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.