Real-time reaction monitoring offers users the ability to control a process, observe chemical and physical phenomena, and possibly elucidate a reaction mechanism. Presented here is the use of colorimetry via image analysis for real-time reaction monitoring of a model system. The selected model system was an acetic acid – sodium hydroxide titration with phenolphthalein as an indicator, which was monitored <i>in situ</i> using time-lapse photography (one frame per second) and red-green-blue (RGB) image analysis using in-house written Python code. Concurrent reaction monitoring of the model system using a pH meter was conducted, with time vs. RGB data and time vs. pH data showing good agreement. Statistical analysis of titration reaction trials showed that reproducible real-time monitoring was achieved.

RGB image analysis for colorimetric real-time reaction monitoring

255th National Meeting (2018)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.