Callisia fragrans (basket plant), is found in many tropical regions, and is used by people in Vietnam as a medicinal herb. Leaves from the plant were extracted with methanol, followed by many chromatography steps to separate the soluble compounds from the plant and isolate active compounds. The crude mass was measured to calculate the concentration. The samples were tested with Pythium ultimum to determine its activity. The active fractions from C. fragrans extracts were separated multiple times by flash chromatography on silica gel. Fractions that gave positive inhibition of P. ultimum growth were eluted with a mixture of ethyl acetate and methanol. So far active fractions have been found in similar areas on the chromatogram after multiple separations using flash chromatography. Compounds that inhibit the growth of P. ultimum have a 90% chance of killing cancer cells.

Purifying potential cancer-inhibiting compounds in basket plant (Callisia fragrans)

255th National Meeting (2018)

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