Functionalization of nanoparticles is significant to explore the applications in experimental therapeutics and toxicological effects in eukaryotic cells. This project is to determine the impact of functionalized silver nanoparticles with acetylsalicylic acid in eukaryotic aquatic organisms such as Daphnia magna. Characterization and functionalization of silver nanoparticles were done using UV spectrophotometer and Dynamic Light Scattering (DLS). Silver nanoparticles, synthetized by a reduction reaction method with Sodium Borohydrate (NaBH<sub>4</sub>) were characterized at 382nm with measurements between 2 to 11nm in size. Functionalization was observed with a shift from 382nm to 406.43nm. Organisms were exposed to solutions of Millipore distilled water, silver nanoparticles, aspirin (325mg), and functionalized nanoparticles. Comparison of the treatments indicate that the survival rate was reduced significantly in organisms exposed to functionalized nanoparticles in 1 hour of exposure. It is suggested that silver nanoparticles enhance the absorption of aspirin by organisms affecting behavior and survival rate.

Effects on the behavior and survival rate of <i>Daphnia magna</i> exposed to silver nanoparticles functionalized with acetylsalicylic acid

255th National Meeting (2018)

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Effects on the behavior and survival rate of Daphnia magna exposed to silver nanoparticles functionalized with acetylsalicylic acid