Aza-Diels-Alder reactions are a dependable method for synthesizing six-membered ring structures in organic synthesis. Danishefsky's diene was reacted with several electron-withdrawing imines in an effort to produce multiple quinolones. Under the reaction conditions, product yields increased with increasing electron-withdrawing strength. Products were purified by column chromatography and characterized by 1D and 2D NMR.

Synthesis and characterization of aza-Diels-Alder products

255th National Meeting (2018)

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