Most scientific studies regarding aurones revolve around their biological activity and using them as a potential medical breakthrough. However, aurones have other interesting properties that could be applied to other fields of science. In particular, aurones are what give yellow flowers their vibrant color, offering clear potential to be used as dyes. Unlike other flavonoids, this application has not been explored. To address this situation, fifteen novel aurones with differing substituents were synthesized and their spectroscopic properties were analyzed using a diode array spectrophotometer. In addition, safety has been screened via toxicology assays. We will discuss the effect of substituents on the absorption maxima, and report the percent inhibition based on cytotoxicity in mammalian cells.

Aurones: Opening doors to a whole new yellow

255th National Meeting (2018)

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