Carbon dots (CDs) doped with nitrogen (N) and sulfur (S) atoms were synthesized in a single step by means of microwave synthesis using citric acid as carbon source in the presence of various amino acids such as lysine, arginine, cysteine, histidine, and methionine. The optical properties and photoluminescence (PL) performance, and quantum yield (QY) of these CDs were investigated by using UV-Vis and Fluorescence spectroscopy measurements at the different pH conditions. These kinds of CDs can great potential in bioimaging and bio-sensing applications. The size of the prepared CDs was analyzed by transmission electron microscope (TEM), and Dynamic light scattering (DLS) studies. Further characterization of CDs were done by zeta potential measurements, thermogravimetric analyzer (TGA) and FT-IR spectroscopy. The blood compatibility of CDs was done by using hemolysis and blood clotting tests. The cytotoxicity of CDs was also investigated using apoptotic and necrotic cell index measurements on the fibroblast and cancerous cell lines.

Amino acids derived multifunctional N-, S-doped carbon dots for biomedical applications

255th National Meeting (2018)

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