Polymersomes (polymer vesicles) are among the most attractive systems for drug delivery applications. We report here an overview on the self-assembly in water of amphiphilic block copolymers into polymersomes, and their applications in loading and controlled release of both hydrophilic and hydrophobic molecules and biomolecules.<br/>We pay special attention to polysaccharide and polypeptide-based block copolymer vesicles and their development in nanomedicine. These copolymers that mimic the structure and some function of glycoproteins on virus represent an example of the effectiveness of a biomimetic strategy in implementing materials design. We especially evidenced the particular benefit of nanoparticles and their multivalency toward the interaction with biological receptors.

Multivalent glycopolypeptide-based micelles and polymersomes

255th National Meeting (2018)

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