Kidney disease as a "silent killer" is influencing more than 10% population worldwide. Thus, developing new imaging techniques that can advance our fundamental understandings of kidney disease progression is critical to early detection of kidney diseases. In this talk, I will present how to take advantage of unique in vivo transport of renal clearable luminescent gold nanoparticles to develop a low cost but high-sensitivity fluorescence imaging technique for kidney functional imaging. The photophysical properties and physiological studies will be presented in the details. The strengths of renal clearable luminescent gold nanoparticles over other fluorophores in the kidney functional imaging will also be discussed.

Fluorescene kidney functional imaging enabled by renal clearable gold nanoparticles

255th National Meeting (2018)

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