Alcoholic steatohepatitis has caused alcohol consumption and the liver damage is due to diet habits of alcohol administration. We investigated the abilities of Molinga oleifera and their components to inhibit liver accumulation of triglyceride. Molinga oleifera leaf was extracted by 70% EtOH and evaluated for alcoholic liver damage prevention. Molinga oleifera leaf extract showed interesting prevention activity. As a results, flavonoids were found from Molinga oleifera extract by HPLC, indicated that, among 7 components, the content of flavonoid was 8.2mg of 3-O-caffeoylquinic acid, 5.0mg of 4-O-caffeoylquinic acid, 6.3mg of multiflorin B and 8.1mg of Quercetin-3-O-ß-D-glucoside. Prevention of alcoholic steatohepatitis was evaluated by histologic data from C57B/L6 mice and liver function was detected by radio isotope 99mTc from SPECT/CT.

Alcoholic liver damage prevention of Moringa oleifera extract

255th National Meeting (2018)

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