Ionic liquids (IL) hold the potential to progressively improve reaction efficiency and cleanliness. ILs support various tenets of green chemistry, including reducing hazardous waste products, ability to be recycled, and reducing additional volatile solvent use. Task-specific ILs have recently received great attention as they have the potential of being not only the reaction media but also catalysts and reagents for chemical transformations. A task-specific ionic liquid, 1-butyl-1-methyl pyrrolidinium hydroxide, that can act both as a reaction medium and a base catalyst, was synthesized. The IL was used as a base catalytic medium for Michael addition reactions using diethyl malonate as the Michael donor. The resultant Michael addition products were purified and analyzed using NMR spectroscopy. This method provides a simple, efficient, and green method for Michael addition reaction with active methylene compounds. The 1-butyl-1-methyl pyrrolidinium hydroxide is currently being used as a base catalyst in the synthesis of biologically active quinolin derivatives.

Task-specific ionic liquid as a base catalyst and a reaction medium for Michael addition reactions

255th National Meeting (2018)

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