Ticks and tick-borne diseases have a major impact on human and animal health worldwide. Nicotinic acetylcholine receptors are targets of highly effective insecticides including neonicotinoids and the recently introduced sulfoximine compounds. Because ticks are resistant against chemical acaricides, we have evaluated the mode of action of several compounds on ticks <i>Ixodes ricinus</i> nicotinic acetylcholine receptors. To test this, we developed new approach using tick membranes from the synganglion and found that it may provide a basis for further studies of the interaction between new acaricides and tick nicotinic acetylcholine receptors.

Evaluating the mode of action of neonicotinoid insecticides and sulfoximine derivatives on <i>Ixodes ricinus</i> nicotinic acetylcholine receptors

256th National Meeting (2018)

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Evaluating the mode of action of neonicotinoid insecticides and sulfoximine derivatives on Ixodes ricinus nicotinic acetylcholine receptors