This presentation will be an account of our research into how Nature rapidly generates molecular complexity. Research in the Lawrence group is primarily focused on the total synthesis of natural products, developing new synthetic methodology, and exploring new strategies and concepts in chemical synthesis. We often take our strategic inspiration from the chemistry of biosynthetic pathways and are fascinated by the origin, structure and function of natural products. The biomimetic approach towards total synthesis allows us to improve synthetic organic chemistry whilst probing fundamental questions regarding the chemistry of biosynthetic pathways. Our research has resulted in the development of several bio-inspired domino reaction sequences that rapidly generate molecular complexity (<i>i.e.</i>, new bonds, rings and stereogenic elements).

Biomimetic natural product synthesis

256th National Meeting (2018)

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