Nanozymes are the catalytic nanomaterials with enzyme mimicking properties. They have attracted great interests recently owing to their unique advantages over natural enzymes and conventional artificial enzymes. Till now, nanozymes have been explored for wide range applications from biosensing and bioimaging to therapeutics and environmental protection. In this talk, I will highlight the recent progress of nanozymes in analytical applications, particularly the work from my own research group. First, I will discuss the in vitro applications, which cover the detection of bioactive small molecules (such as hydrogen peroxide and glucose), nucleic acids, protein biomarkers, cells, etc. Second, I will discuss the in vivo applications, which include the monitoring of bioactive small molecules (such as glucose and lactate) in live brains and tumor tissues, the evaluation of drug efficacy (such as astaxanthin for cerebral ischemia), and the investigation of drug metabolism (such as heparin metabolism), etc.

Nanozymes for in vitro detection and live bioassays

256th National Meeting (2018)

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