Pesticide drift, which is the off-target movement of pesticides, is recognized as a major cause of pesticide exposure affecting people as well as wildlife and the environment. During agrochemical discovery lead optimization, it is important to assess the vapor movement for analogs in lab-greenhouse and to better predict possible off-target movement for field candidates with potential volatility concern in field studies. Solid phase microextraction (SPME) is one of the most important solvent-free methods of sample preparation innovative techniques – simple, fast and efficient for organic compounds from gaseous, aqueous, and solid matrices. SPME method has been developed and applied in several Discovery insecticide and herbicide lead areas to assess volatilities for analogs and formulations along with bioassays. This poster will focus on applying SPME to a Discovery Herbicide lead area to assess the impact of different formulations on the volatility of sprayed moist and dry soils and on the volatility of sprayed glass plates on indicator plants. The results showed SPME is a simple and useful tool to identify potential volatility issues in discovery lead optimization.<br/>

Use of solid phase microextraction (SPME) in assessing volatility in agrochemical discovery lead optimization

256th National Meeting (2018)

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