Rapid access to pure glycans by automated glycan assembly (AGA)1 allows now for the rapid assembly of polysaccharides as long as 50-mers2 using a commercial synthesizer.3 These synthetic polysaccharides can be combined much like “molecular LEGO” 4 to create even larger oligosaccharide assemblies to address fundamental questions of carbohydrate structure, folding and material science applications. The synthetic work is combined with molecular modelling calculations and physical methods to characterize carbohydrate structure.

Novel materials created from synthetic polysaccharides: Synthesis, structure and function

256th National Meeting (2018)

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