Breast cancer is the most common cause of cancer death among women (40,610 deaths in 2017 in the USA alone), one in four women with cancer has breast cancer. According to U. S. Breast Cancer Statistics, about 1 in 8 U.S. women (about 12%) will develop invasive breast cancer over the course of her lifetime. Thus, there is an urgent need to develop easy, cost effective, suitable devices that can detect breast cancer cells at their early stage. By this facile and green approach for the synthesis of highly fluorescent, water soluble antibody conjugated multicolor nanprobes derived from naturally available popular tropical fruits Mango and Prune we can detect highly aggressive Triple negative breast cancer cells (TNBC). These nanoprobes have the capability to track breast cancer heterogeneity via selective separation and accurate identification of TNBC and the human epidermal growth factor receptor 2 (HER-2) or the Estrogen receptors (ER) and the Progesterone receptors (PR) breast cancer cells from the mixture.

Fruit based green synthesis of multicolor nanoprobes for tracking breast cancer heterogeneity

256th National Meeting (2018)

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