Amylose tris(3,5-dimethylphenylcarbamate) is one of the most useful helical polymers as the chiral stationary phase.  We investigated molecular structure of linear and cyclic ADMPC in solution to determine their local conformation and furthermore to clarify the mechanism of the chiral separation.  SAXS measurements for ADMPC samples were thus made in some organic solvents to determine their local helical structure and chain stiffness.  Cyclic ADMPC has locally more extended helical structure and less chain stiffness comparing with linear ADMPC in the same solvent.  Chiral separation behavior of cyclic ADMPC is also appreciably different from those for the linear ADMPC.

Conformation and chiral separation behavior of linear and cyclic polysaccharide derivatives

256th National Meeting (2018)

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