A better understanding of how molecules interact in aqueous solutions has ramifications across the biosphere, lithosphere, atmosphere, and hydrosphere. It hence impacts all the major areas of the sciences. For example, aqueous solutions of dissolved organic molecules and salts are central to biology and biochemistry. How water interacts with organic molecules is frequently discussed under the rubric of the hydrophobic effect, whilst how salts influence these solutions pertain to what is known as the Hofmeister effect. Our recent studies into the supramolecular interactions behind these two effects have utilized deep-cavity cavitands as models, and this presentation will emphasize how simple 1:1 complexes with these hosts can be used to probe the Hofmeister effect, as well as the equally puzzling reverse Hofmeister effect.<sup>1</sup>

The Hofmeister and inverse Hofmeister effects

256th National Meeting (2018)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.