As reflected in the EPA Environmental Fate and Effects Division (EFED) guidance for addressing unextracted residues in laboratory studies, residues that are weakly sorbed to solid matrix and thus available for degradation, should be adequately extracted in order to quantify the degradation and to avoid double-counting their sorption in exposure models. Additionally, transformation products may be less polar or more polar than the parent compound and may interact with the soil or sediment differently. Therefore, soil extraction regimes should include both polar and nonpolar solvents or solvent mixtures with a sufficiently wide range of chemical properties. At Innovative Environmental Services (IES) Ltd, Switzerland, an independent GLP-certified contract research organization, several GLP degradation studies have been conducted, for which soil extraction regimes included additional solvents in order to cover a wide solvent polarity range. The objective of this poster will be the presentation of soil extraction results for several degradation studies, possibly accompanied by correlation to the chemical characteristics of test items and transformation products.

Degradation studies: Solvent systems including both polar and nonpolar solvents to extract residues from soil matrix

256th National Meeting (2018)

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