Chirality is very common in nature and can occur at different scales such as molecular, macromolecular, supramolecular and material level. In supramolecular assembly, the chirality is not only determined by the molecule component itself, but also largely relies on the spatial arrangement of the component molecules through non-covalent interactions. Here, we designed a square-like metallomacrocycle which tended to form twisted helical nanoarchitectures through hierarchical self-assembly. When cholesterol was introduced as chiral component, the helical nanoarchitectures displayed one-handed arrangement, followed by the gelation process. Both 1D and 2D NMR spectroscopy, electrospray ionization mass spectrometry (ESI-MS), traveling-wave ion mobility mass spectrometry (TWIM-MS) have been used to characterize the supramolecules. And scanning electron microscopy (SEM), transmission electron microscopy (TEM), circular dichroism (CD) microscopy are utilized to characterize the helical nanostructures.

Self-assembly of chiral helical nanostructures based on cholesterol-aided metallomacrocycle

256th National Meeting (2018)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.