This presentation will focus on the state-of-the-art of the monitoring of cyanotoxins using advanced electrochemical biosensors. Most of the discussion will focus on the detection of selected cyanotoxins, including microcystin isoforms, cylindrospermopsin, saxitoxins and anatoxins. The overview will include discussion on electrochemical biosensor approaches using advanced biomolecules and transducers. Emphasis will be placed on environmental aptasensors to detect cyanotoxins which exhibit lower limits of detections than the conventional analytical procedures and other types of biosensors. Details will be provided on the importance of optimization steps towards an overall increase of sensitivity of aptamer-based biosensors. The role of selected parameters of biosensor components, the chemistry of assays and procedures, and their effect in limit of detections will be discussed in relation to sensor selectivity and sensitivity. Examples of recent advances in aptasensors specific to cyanotoxins will be presented and relevant mechanistic concepts and interfacial phenomena will be elucidated. Finally, challenges on the development of highly sensitive and selective biosensors for the detection of cyanotoxins in field water samples as well as for on-line monitoring will be discussed.<br/>

Advances in the field of biosensors for the environmental monitoring of cyanotoxins

256th National Meeting (2018)

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