Quality assurance of raw materials used in the production of a veterinary topical analgesic was completed for Hobart Laboratories using a variety of analytical techniques. Certain analytical techniques were examined and then optimized for the most efficient way to test the raw materials. For example, the Non-Volatile Matter Test, which measures the amount of volatile matter using an oven with proper ventilation, has been shown to be effective yet time consuming. To improve efficiency and reduce assay time, a moisture analyzer was used. Although it has poor ventilation it heats up quicker and is more precise. A drawback of this method is that the amount of sample loaded into the Moisture Analyzer is too small, thus not being a prime representation of the material itself. To combat this, the number of analyzed samples per stock material from 3 to 5 was increased. After the purity of each of the raw materials was validated by the tests, certificates of authenticity were produced and presented to Hobart Laboratories. These certificates indicated that each of the raw materials’ characteristics were within the acceptable range of industry.

Optimization of the analysis of raw materials in a veterinary topical analgesic

2019 Spring National Meeting

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