Over the past two decades, the transition metal catalysed addition of boron-element (B-E, where E = H, B, Sn, Si, etc) bonds to unsaturated compounds has received a considerable amount of attention. Given the intensity of interest in the reactivity of B-E bonds it is somewhat surprising that relatively little is known about the analogous addition chemistry of compounds containing single B-E bonds where E is phosphorus. The corresponding phosphinoboration would introduce a P-C bond and a reactive B-C bond that could be further elaborated to provide access to a host of useful structural motifs and, in this regard, is a worthy target. We have initially reported on the synthesis of phosphinoboronate esters containing a single P-B bond along with the corresponding reactivity studies towards a range of organic substrates including aldehydes, aldimines, alkynes and allenes. We report herein on our latest findings of these remarkable main-group compounds and their reactivity with late metal complexes.

To B-E or not to B-E? The phosphinoboration reaction

2019 Spring National Meeting

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