The first line of defense against bacterial infections tend to be antibiotics. Although antibiotics have been proven effective in treating these type of infections, bacteria have the ability to develop resistance to these antibiotics. Silver nanoparticles are known to have intrinsic antimicrobial properties and are being studied as potential supplements or replacements for traditional antibiotic treatments. This study was conducted to investigate the synergy between silver nanoparticles and various antibiotics on the growth of the gram-negative bacteria <i>Escherichia coli. </i>Cultures were incubated in tryptic soy broth and Phosphate Buffered Saline with serially diluted concentrations of varied antibiotics and silver nanoparticles synthesized by sodium citrate reduction of silver nitrate. Using UV-Vis spectrophotometry the growth of bacteria was quantified after several hours. A well diffusion method was used to determine the potential antimicrobial abilities of the nanoparticles. Evidence of a synergistic interaction between silver nanoparticles and antibiotics was observed.

Analyzing synergistic interactions between silver nanoparticles and antibiotics: Implications for microbial growth

2019 Spring National Meeting

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