Bacterial nanocellulose (BNC) is a highly pure and peculiar form of cellulose, with an important role in the preparation of new functional and sustainable nanomaterials.<sup>1</sup> Over the last years, the study of BNC in the field of drug delivery and skin regeneration has been significantly recognized, in particular as a drug carrier for transdermal administration and as wound healing membranes. Herein, the use of bacterial nanocellulose membranes is coupled with the layer-by-layer assembly of natural biopolymers, namely chitosan and sodium alginate, for the design of a bioactive nanostructured film for skin regeneration. Specifically, the layer-by-layer assembly of oppositely-charged polyelectrolytes into oxidized BNC membranes is presented, with particular emphasis on strategies for tuning the loading and release of dexpanthenol (the selected drug) in/from the polyelectrolyte multilayer BNC nanofilms.<br/>

Multilayered nanocellulose based systems for skin regeneration

2019 Spring National Meeting

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