18-Hydroxycorticosterone is an important marker for several pathological conditions, such as Corticosterone Methyloxydase Deficiencies (CMO-II) and Primary Hyperaldosteronism. It is an intermediate in the aldosterone synthesis in the body. Measurement of 18-Hydroxycorticosterone is known to be challenging, as this steroid is unstable. Accurate testing of 18-Hydroxycorticosterone is critical to ensure successful patient outcomes. This poster presents the synthesis and development of a Certified Reference Material (CRM) of high purity 18-Hydroxycorticosterone.

Synthesis and development of a certified reference material of 18-hydroxycorticosterone

2019 Spring National Meeting

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