Janus particles are interesting materials due to their inherent dual face properties. Having different functions and properties on a single particle allows these materials to be used for drug delivery and interfacial chemistry. Silica polypeptide composite Janus particles are unique because they are stimuli-responsive particles consisting of an inorganic colloidal silica core half of which is coated in chromium and the other half is coated with an organic polypeptide shell. The responsive nature comes from the polypeptide shell consisting of the homopolypeptide, poly (ε-carbobenzyloxy-L-lysine) (PCBL), which is known to exhibit a reversible coil-helix transition when dissolved as a pure polymer in m-cresol. With addition of the polypeptides to the silica core, these Janus particles can be used to study the polypeptide transition and other surface chemistry reactions at the organic/aqueous interface.<br/>

Silica polypeptide composite Janus particles

2019 Spring National Meeting

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