Magnesium is an essential cation for multiple processes in the body. The amount of magnesium in the body should be constant over a 24-hour period. Since it is the kidney that regulates the balance of magnesium in the body, any fluctuations can be linked to issues with the kidney itself; such as chronic renal diseases. Recently, there has been a re-evaluation of the utilization of magnesium levels in the urine to assess chronic kidney disease and end-stage renal disease. The classic techniques for magnesium determination using colorimetric methods are known to have interferences and limitations. In our lab, we have studied the use of conductiometric titrations to determine the amount of sulfate present in urine. We have found the technique to be relatively rapid, inexpensive and the results are as accurate as the classic techniques for sulfate determination. Due to our recent results studying sulfate, we are investigating the utilization of conductiometric titration methods for magnesium determination in urine and will compare the results to the classic colorimetric methods.

Advanced urine testing using conductiometric techniques to assess renal function

2019 Spring National Meeting

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