A series of polyamide carboxylate nanoparticles were prepared by the reaction of amine containing molecules with anhydrides. For example Tris was reacted with gluctaric anhydride, DTPA dianhydride and EDTA dianhydride to form a series of amide carboxylic acids. The hydroxyl groups of Tris were then crosslinked in the presence of base and surfactant to form nanoparticles that were characterized spectroscopically, by dynamic light scattering, and TEM. The nanoparticulate products bind metal ions and have the potential to serve as catalysts, composite materials, and diagnostic agents in clinical applications. The breadth and simplicity of the production of amide carboxylate nanoparticles, particle characterization, and applications are described.

Amide-carboxylate oligomeric nanoparticles for metal ion binding

2019 Spring National Meeting

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