<b> </b>The merits of continuous processing over batch processing are well known in the manufacturing industry. Continuous operation results in shorter process times due to omission of hold steps, higher productivity due to reduced shut down costs and lowers labor requirement. This talk will aim to elucidate how continuous processing can make a meaningful impact on the cost of manufacturing of biotherapeutic. Our recent experience with creating continuous platforms for both microbial fermentation and mammalian cell culture processes will be used to elucidate on the following points. What kind of productivity gains can continuous processing offer? How would one aim to monitor and control a continuous process? What are the key challenges in creating a continuous process? What is the net impact on COGS?

Continuous processing of biotech therapeutics Ð enabling case studies

2019 Spring National Meeting

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