The oxidative and dehydrogenative coupling reactions have been an area of great interest in the past few years. They have emerged as one of the most important strategies for the development of new and greener synthetic methodologies in organic synthesis in recent years. Several precious metals such as palladium, platinum and ruthenium were previously used to carry out these reactions. However, the use of non-precious metals such as cobalt, manganese and nickel is still limited. In this current study, we would like to report the successful use of nickel metal as catalysts for oxidative esterification of cyclohexene and its derivative with various carboxylic acids followed by insitu reduction. In our attempts to carry out the reaction by reacting benzoic acid with cyclohexene in presence of NiBr2 (10 mol%) and Di tert-butylperoxide (as oxidant), moderate to good yields of the product was obtained.

Ni-catalyzed oxidative esterification of allylic sp3-carbon followed by in situ reduction

2019 Fall National Meeting

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