Selective estrogen receptor modulators (SERMs) are a class of compounds utilized in the treatment of breast cancer. Unfortunately their use is limited by side effects due to unfavorable estrogenic activity in other tissues. An ideal SERM would inhibit mammary carcinogenesis while maintaining positive estrogenic activity in the brain, bone, and fatty tissues. Herein, we report the design and progress towards the synthesis of a novel SERM.<br/>

Synthesis of an ideal selective estrogen receptor modulator

2019 Fall National Meeting

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