The goal of the Payne Lab at Duke University is to understand how cells and proteins interact with nanoscale materials and then use this understanding to control cellular properties. This talk will focus on the imaging methods used to understand the cellular response to titanium dioxide nanoparticles. We have recently determined that titanium dioxide nanoparticles, widely used in consumer products, lead to a unique oxidative stress and epigenetic response in human cells. A combination of fluorescence microscopy and electron microscopy is used to understand how cellular uptake and transport of these nanoparticles generate this nuclear-level response.

Imaging the cellular response to TiO<sub>2</sub> nanoparticles

2019 Fall National Meeting

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Imaging the cellular response to TiO2 nanoparticles

Imaging the cellular response to TiO₂ nanoparticles