Generating Disease Insights on Patient Journey, Treatments and Outcomes by Use of Global Hospital Network EHR.

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Abstract

Objective: Generating patient population analytics using patient data from globally networked hospitals for insights into patient journey, treatment efficacy and outcomes, using examples of asthma, multiple myeloma and SARS-CoV-2 (COVID-19).

Method: The research used anonymised patient EHR data from a hospital network comprising 30 M patients in 68 sites, worldwide. The query used 5 dimensions of EHR data: demographics, diagnoses, medications prescribed, laboratory results & procedures performed; receiving aggregated results in return.

Results: Using an EHR-based patient data network, users can generate insights on the patient journey, treatments and outcomes by applying informatics methodologies to extract and interpret information from large amounts of electronic health records. This allows a focused search of patient characteristics or treatment patterns, and enables patient, physician and site outreach. Query of the global EHR network generated data on Asthma, Multiple Myeloma and COVID-19.

Conclusion: An EHR-based patient data network can allow the interrogation of retrospective data, as well as the generation of new prospective data for RWE studies, surveillance, sentinel and cross-sectional studies, feasibility studies, screening for risk management or health-care system evaluation, among other traditional or innovative study designs.

Keywords

health data

rwe

real-world evidence

multiple myeloma

asthma

covid-19

patient data analytics

patient population analytics

real-world data

rwd

real world insights

patient journey

patient outcomes

ehr

emr

coronavirus

abdominal pain

acids, carbocyclic

alkaloids

amino acids

amino acids, aromatic

amino acids, cyclic

amino acids, peptides, and proteins

analysis

anemia

antibodies

apnea

atropine derivatives

aza compounds

azabicyclo compounds

back

back pain

bacterial infections and mycoses

belladonna alkaloids

biological products

blood

blood protein disorders

blood proteins

bodily secretions

body fluids

body regions

bone and bones

bridged bicyclo compounds, heterocyclic

bronchial diseases

bronchitis

cancer

carbohydrates

carboxylic acids

cardiovascular diseases

cardiovascular system

cells

chemical actions and uses

chemical phenomena

chemistry techniques, analytical

chest pain

colon

complex mixtures

conjunctival diseases

conjunctivitis

constipation

coronaviridae

cyclophosphamide

dander

data collection

dermatitis

dermatologic agents

dexamethasone

diagnosis

diagnostic techniques and procedures

diagnostic techniques, urological

diet, food, and nutrition

digestive system

digestive system diseases

dimensions

disease

diseases

drug therapy

dyspepsia

electronic health records

emollients

eosinophilia

epidemiologic methods

esophageal diseases

esophagitis

extracellular fluid

eye diseases

facial bones

fatigue

filtration

fluids and secretions

food

food and beverages

fused-ring compounds

gastroenteritis

gastrointestinal diseases

gastrointestinal tract

globulins

glomerular filtration rate

growth substances

heart

hematologic diseases

hemic and immune systems

hemic and lymphatic diseases

hemorrhagic disorders

hemostatic disorders

heterocyclic compounds

heterocyclic compounds, 1-ring

heterocyclic compounds, 2-ring

heterocyclic compounds, bridged-ring

heterocyclic compounds, fused-ring

hydrocarbons

hydrocarbons, halogenated

hypersensitivity

hypersensitivity, immediate

hypertension

immune system diseases

immunoglobulins

immunoproliferative disorders

immunoproteins

infection

innovation

intellectual property

intestine, large

intestines

investigative techniques

ipratropium

isoindoles

kidney function tests

leukocyte disorders

lower gastrointestinal tract

lung diseases

lung diseases, obstructive

lymphoproliferative disorders

management

medical records

medical records systems, computerized

melphalan

micronutrients

models

muscle

musculoskeletal system

mustard compounds

nasal septum

neoplasms

neoplasms by histologic type

neoplasms, plasma cell

nervous system diseases

neurologic manifestations

neuromuscular manifestations

nidovirales

nitrogen mustard compounds

nose

nose diseases

nutrients

organic chemicals

organophosphorus compounds

otorhinolaryngologic diseases

pain

paranasal sinus diseases

paraproteinemias

pathologic processes

pathological conditions, signs and symptoms

pharmacologic actions

pharyngeal diseases

pharyngitis

phenylalanine

phosphoramide mustards

phosphoramides

phthalic acids

phthalimides

physical phenomena

physiological effects of drugs

physiological phenomena

piperidines

piperidones

plasma

polycyclic compounds

prednisone

pregnadienediols

pregnadienes

pregnadienetriols

pregnanes

proteins

pyrimidines

radiology

records

reproductive and urinary physiological phenomena

researchers

respiration disorders

respiratory hypersensitivity

respiratory system

respiratory tract diseases

respiratory tract infections

rhinitis

risk

risk management

rna viruses

serum globulins

signs and symptoms

signs and symptoms, digestive

signs and symptoms, respiratory

sinusitis

skeleton

skin and connective tissue diseases

skin diseases

skull

sleep

sodium

solanaceous alkaloids

spasm

speed

steroids

steroids, fluorinated

stomatognathic diseases

surveillance

syndrome

thalidomide

therapeutic uses

therapeutics

torso

trimethoprim

tropanes

turbinates

urinary tract physiological phenomena

vaccines

vascular diseases

viruses

vitamins

volume