The development of materials with co-immobilized enzymes that would advance new greener routes for the syntheses of pharmaceuticals and provide enantio-selectivity of substrates resulting in limited number of side products of biologically active compounds is the basis of this study. Successful entries into biocatalytic processes requires both biochemical and materials chemistry skill sets making this study highly collaborative focusing on creating new biocatalysts through co-immobilization of glucose oxidase (GOx) and chloroperoxidase (CPO) onto metal-organic frameworks (MOFs) to produce high-value pharmaceutical synthetic strategies. Creating robust and efficient biocatalysts of this nature could positively impact pharmaceutical organic syntheses by replacing hazardous solvents with greener chemistries.

Enzyme immobilization on metal-organic frameworks to facilitate greener chemistries

ACS Spring Meeting 2021

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.