Photodynamic therapy (PDT) has potential use in the treatment of cancer and other health disorders. PDT utilizes light and a photosensitive agent that once activated by light, generates singlet oxygen that affects surrounding cells. The goal of this research was to synthesize and characterize the novel photosensitive agent, H2TPP-3-Amino-1,2-Propanediol. The H2TPP-3A12P was purified using column chromatography and characterized using IR, UV-Vis, and NMR spectroscopies. Purity was determined using high-performance liquid chromatography. Cytotoxicity testing of the H2TPP-3A12P using A549 lung cancer cells in light and dark conditions determined that this novel material has potential as a next generation PDT agent.

The photodynamic therapy potential of a novel water-soluble porphyrin

ACS Spring Meeting 2021

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.