Ascorbic acid (Vitamin C) can be used as a substrate or mediator in organic synthesis. This study illustrates the application of ascorbic acid as a catalyst/mediator in organic synthesis. Ascorbic acid-based catalytic system is economical, non-toxic, and readily available. Given the current trend of conducting organic reactions under environmentally benign conditions, ascorbic acid-catalyzed transformations are highly worthful. Remarkably, a wide range of reactions is successfully conducted with ascorbic acid-catalyzed reactions. In many cases, the processes' pertinent mechanism is advanced to explain the formation of the products.

Significant role of ascorbic acid in organic synthesis

ACS Spring Meeting 2021

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