Synthesis of superparamagnetic nanoparticles (SMNPs) in a colloidal form is of rapidly increasing interest due to their scope of unique chemical and physical properties which make them suitable for a host of applications, with a primary focus being their use in biomedicine. One specific application is magnetic hyperthermia, which involves targeted cancer cell necrosis by heat generation of SMNPs placed in a localized alternating magnetic field. For magnetic hyperthermia uses, there is a requirement that these SMNPs have a narrow particle size distribution while maintaining high magnetization, complete biocompatibility, and ease of surface modification. Synthesis of gold-coated iron cobalt nanoparticle based ferrofluid has the potential to provide SMNPs with these properties while potentially offering higher magnetization and alternate biocompatibility methods than that demonstrated by iron oxide nanoparticles. The details of the synthesis and characterization will be presented.

Superparamagnets for magnetic hyperthermia applications

ACS Spring Meeting 2021

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