Botanical dietary supplement (BDS) industry is a fast-growing multi-billion-dollar industry that faces many quality-related challenges in ensuring product safety in the marketplace. BDSs are advertised as being more "natural" and "safer" than isolated or synthesized chemicals and therefore fit the modern lifestyle trend. However, because BDSs are legally considered as foods in many territories such as India, the European Union, New Zealand, and the USA, they do not require, as with drugs, premarket approval and safety/effectiveness assessment in these areas. Due to the development of globalization and online trading platforms, economically motivated adulteration in BDSs has a great chance to occur when the products are transported between different countries. Because of the complexity and continuous development of BDS products, the detection of adulteration is often accomplished using an orthogonal approach via multiple analytical technologies, ranging from macro-microscopic examination to DNA-based, spectroscopic, and chromatographic testing. This presentation will overview adulteration detection strategies by demonstrating real case studies in an industrial setting.

Detection of adulteration in botanical dietary supplements: Analytical strategies for finished product/ingredient quality control

ACS Spring Meeting 2021

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