Glycans play critical roles in the biology of infectious diseases and have been well studied as receptors of pathogens. Their role in host-response mechanisms to infection is less well studied. It is becoming increasingly clear that glycans dynamically change upon infection in ways that directly impact the immune response. This talk focuses on decoding structure-function relationships in the glycome related to pathogen host-response. It will focus on our latest work on influenza and bacterial sepsis.

The sweet side of host-response

ACS Spring Meeting 2021

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