<br/>Glycans offer cells a rich coding space, enabling the encoding of cellular information, such as cell state (Signal). However, their position at the outer edge of cells makes them a target for pathogens, requiring variation to be added to the code to avoid being targeted (Noise). This leads to a system in which the sugar code (i.e. the glycan motifs controlling function) is hidden within the noisy milleu of larger heterogenous glycan structures. This talk focuses on use of high-throughput analytical methods, including our lectin microarray technology and newly developed miRNA-proxy approach, in tandem with data integration, to decode structure-function relationships in the glycome. Our work is identifying glycan drivers of disease, focusing on clinical samples and relevant systems.  The talk will discuss our latest work in this area.

Decoding the Glycome

ACS Spring Meeting 2021

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.