Catalytic activity of copper(I) complexes supported by phenanthroline-containing catenane ligands towards a new C(sp3)–O dehydrogenative cross-coupling of phenols and bromodicarbonyls is reported herein. After interlocking the phenanthrolines by the strong and flexible mechanical bond in the catenane, the Cu(I) catalytic center is kinetically stabilized with a thermodynamically identical ligand. By employing the mechanically interlocked ligands (MILs), the active catalyst with an open copper coordination site can be revealed only transiently and the stable, coordinatively saturated Cu(I) pre-catalyst is quickly regenerated after substrate transformation. Compared with a control Cu(I) complex supported by non-interlocked phenanthrolines, the catenane supported Cu(I) is highly efficient with a broad substrate scope, and can be applied in gram-scale transformations without a significant loss of the catalytic activity. This work demonstrates the kinetic stabilization to Cu(I) from the catenane ligands that provide a dynamic and responsive copper coordination sphere, highlighting the potential of the mechanical bond as a design element in transition metal catalyst development.

Kinetically Stabilized Copper-Catenane Complex in C-O Cross-Coupling Reactions

In order to view the entire gallery of posters, videos, and other materials, please click "Submissions" below.

To find the Q&A for each poster category, please click "Sessions" below. To ask a question, simply click on the category session; they are organized alphabetically by title. After clicking, you'll see a list of video presentations in the list to the right. Below each video area, you'll see a section entitled 'Q&A for this presentation:'. Here you'll be able to post questions to the authors. They'll be notified, and you'll also be notified when they reply to your question. You can expect that notification by email, and you'll find the author's response here. 

ACS Publications Symposium

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.