Background
Serious myocardial ischemia reperfusion injury (MIRI) after percutaneous coronary intervention (PCI) could worsen the myocardium damage and cardiac function than pre-operation. The corresponding echocardiographic characteristics and hemodynamic changes is still unknown.
Method(s)
Patients underwent emergency primary PCI were evaluated by regular and speckle tracking echocardiography before (within 8 hours) and after (within 2 hours) the operation. Coronary territory specific strain (CTSS) of the recanalized vessel was calculated on the basis of the perfusion territories of the three major coronary arteries in the 17-segment LV model. Patients with serious arrhythmia, no-reflow or slow-reflow, chest pain, abnormal elevation of ST segment after PCI were identified as clinical MIRI. Data were compared between patients with and without clinical MIRI.
Result(s)
There was no difference in left ventricular diameter or myocardial thickness between groups either before or after PCI. Patients without clinical MIRI showed significantly increased eject fraction (EF), global longitudinal strain (GLS) and CTSS，while patients with clinical MIRI demonstrated decreased GLS and CTSS but unchanged EF. The percentage changes of EF, GLS and CTSS of the two group were: PCI without MIRI vs. PCI with MIRI, %∆EF: 10.4±2.9% vs. -2.2±2.3%; %∆GLS: 11.2±4.5% vs. -13.0±7.8%; %∆CTSS: 13.0 ±7.1% vs. -30.3±12.3%; all P<0.05. The areas under ROC curve and cut-off values of these parameters were %∆EF: 0.812, 4.8%; %∆GLS：0.853, -7.1%; %∆SLS: 0.881, -9.6%, all P<0.01.
Conclusion(s)
Changes of EF, GLS and CTSS after PCI can detect MIRI, among which the CTSS showed the best diagnostic value.

Application of coronary territory specific strain in evaluation of myocardial ischemia reperfusion injury after percutaneous coronary intervention

ECHO ASIA is organized by Asian-Pacific Association of Echocardiography (AAE). The meeting combines the basic echocardiography training curriculum and the state-of-the-art lectures/scientific sessions provided by international as well as Asian-Pacific experts. The meeting is a unique forum where scientists from many countries in the Asian-Pacific region who are involved in the field of Doppler echocardiography gather together to exchange knowledge and skills. Various internationally distinguished faculties consent to present their findings and reveal their clinical experiences in ECHO ASIA.