To date, there is no outcome set available for psoriasis from a patients’ perspective. Psoriasis is a common chronic inflammatory skin disease and significantly impacts patients’ quality of life. Seeing that this disease has such a high impact, it is essential that the patient’s voice is incorporated into its management. The purpose of this study was to develop an outcome set for daily clinical practice which was solely defined by psoriasis patients. First, a systematic review was conducted, providing an overview of all patient-relevant outcomes defined in current literature. These outcomes were presented to 10 patients, using a nominal group technique, to examine whether these results represented all of their relevant outcomes. Afterwards, these outcomes were ranked by 120 patients attending our psoriasis clinic. Patients were asked to rank cards, containing the outcomes and a brief explanation of that particular outcome, in order of their perceived importance. Finally, a literature review was performed to assess which instruments are available to evaluate the outcomes in our outcome set. The systematic review resulted in 23 patient-relevant outcomes. After the nominal group meeting, two outcomes were excluded as they were deemed inappropriate. The outcomes found most important by psoriasis patients were symptom control, treatment efficacy, confidence in care and control of disease. The least important outcomes were comorbidity control, productivity and cost of care. Based on this ranking exercise an outcome set was defined. The review provided us with instruments for each outcome. In conclusion, we defined the first patient-driven outcome set that enables us to evaluate value for patients when managing psoriasis in clinical practice. This set defines treatment success, based on what is truly important to the patient. In addition, it may also serve as a benchmarking tool to critically appraise and improve the care delivered across centers and amongst individual healthcare providers.

ESDR071 - Creating Value for Psoriasis Patients: Development of a patient-driven Outcome Set for Clinical Practice

50th Annual Meeting of the European Society for Dermatological Research. VIRTUAL MEETING