The autoimmune pemphigus has high risk of cutaneous bacterial infection which may be crucial for further development and prognosis of the disease. The objective was to examine bacterial microbiota in autoimmune pemphigus.18 women aged 57.5±0.5 suffered from autoimmune pemphigus. 13 patients suffered from pemphigus vulgaris,4 from seborrheic pemphigus, 1 from pemphigus vegetans. Every patient had more than 2 lesions. The bacteriological examination was performed in different areas of the skin. The scalp lesions in 2 patients with seborrheic pemphigus were contaminated by St. aureus. The oral mucosal lesions in 9 patients with pemphigus vulgaris were contaminated by Enterococcus hirae. The breast lesions were contaminated by St.aureus in 2 patients with pemphigus vulgaris and 2 patients with seborrheic pemphigus, St.co and E. faecalis- in 1 patient with pemphigus vulgaris. The abdomen lesions were contaminated by St.aureus in 1 patient with pemphigus vulgaris, E. faecalis in 1 patient with pemphigus vegetans. The groin skin was contaminated by St.co in 1 patient with pemphigus vulgaris, E.coli in 1 patient with pemphigus vulgaris, E. faecalis in 1 patient with pemphigus vulgaris, St.co and E. faecalis in 2 patients(including a patient with pemphigus vegetans). The hip skin was contaminated by St. aureus, E. faecalis, E.coli., E. aerogenes in a patient with pemphigus vegetans. Finally, bacterial microbiota in pemphigus is rather diverse and conditionally pathogenic may transfer to pathogenic in autoimmune disease.

ESDR091 - Bacterial microbiota in autoimmune pemphigus

50th Annual Meeting of the European Society for Dermatological Research. VIRTUAL MEETING